The Prevalence of Escherichia coli Derived from Bovine Clinical Mastitis and Distribution of Resistance to Antimicrobials in Part of Jiangsu Province, China

Bovine mastitis is often taken as one of the most common diseases in dairy farms, which its pathophysiology leads to a reduction milk production and quality. The penetration pathogenic bacteria into mammary gland, through either contagious or environmental approach, has been determined way infection. derived have become challenge practice, since increasing exposure antimicrobial. In order identify characteristics epidemiological regulation drug resistance bovine northern Jiangsu, 156 clinical samples were collected from 3 large-scale farms for investigation analysis E. coli. positively isolated total 143 samples. results showed that 78 strains coli detected, with prevalence rate 26.99%, followed by 67 K. pneumoniae, 23.19%, 38 Staphylococcus, spp. 13.15%. addition, tested susceptibility 8 kinds antibiotics. It was shown gentamicin tetracycline effective against coli, 83.3%, streptomycin ciprofloxacin, 73.1% 71.8% respectively. However, β-lactams including penicillin, cefothiophene, amoxicillin serious isolates. There 12 genes detected PCR, β-lactam (blaTEM, blaCTX-M, blaSHV), aminoglycoside (armA armB), (tetA, tetB, tetC), quinolone (qnrS, qepA, oqxA, oqxB) related genes. Notably, all isolates carried blaTEM gene (100%). detection blaCTX-M 53.8%, blaSHV (20.5%), armA (9.0%), tetA (26.9%), tetB (2.6%), tetC qnrS (29.5%), oqxA (37.2%) oqxB (1.3%). present study provides crucial information on distribution bacterial pathogens Jiangsu province, well highlighting antimicrobial might help improve efficiency antibiotics treatment mastitis.